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He & She MD vs TMates

He & She MD and TMates compared on real monthly cost, medications, states served and how each one verifies.

By Sam Reed · Founder and data lead
TL;DR — our verdict
He & She MD rates higher at 7.9/10.
He & She MD
7.9/10
$149per month, from
-$50/mo vs TMates
VerifiedVisit He & She MD
TMates
7.8/10
$199per month, from
+$50/mo vs He & She MD
VerifiedVisit TMates

Every line that matters

He & She MD
TMates
Month-1 price
$149
$199
Month-2+ price
$149
$199
Three-month total
$447
$597
Membership fee
None
Not disclosed
Consultation fee
None
None
Shipping
Free
Free
Medications
Compounded semaglutide, Compounded tirzepatide
Compounded semaglutide, Compounded tirzepatide
Forms
Injection
Injection
Medication type
Compounded only
Compounded only
States served
49 states
45 states
Insurance
No
Yes
Partner pharmacy
Not disclosed
Not disclosed
LegitScript badge
Yes
Not disclosed
Cancel anytime
Not disclosed
Yes
Our rating
7.9 / 10
7.8 / 10
Start today
Visit He & She MD
Visit TMates
= better value on that rowScroll sideways on small screens — the first column stays pinned

Real cost over three months

An introductory month makes a programme look cheaper than it is. This is the first month plus two at the standing rate, which is where the two actually separate.

He & She MD
Month 1
$149
Months 2–3
$149 × 2
Three-month total
$447
TMates
Month 1
$199
Months 2–3
$199 × 2
Three-month total
$597
Quick pick

Which one is you?

Choose He & She MD if…
  • Users who want a true monthly plan before committing to a prepaid one
  • A true monthly plan with no commitment ($199/mo semaglutide)
  • Charged only if a provider prescribes
  • Pharmacy partner and chief medical officer are named
Choose TMates if…
  • Users with insurance who want a coached GLP-1 program with multiple medication options
  • One of the few GLP-1 providers that accepts major insurance
  • Flat-rate pricing includes meds, consults, coaching, and delivery
  • 24/7 SMS-based coaching and digital check-ins
Safety

How both check out

He & She MD
Verified

Partner pharmacy: Not published

LegitScript: Certified · FDA letters: none on file

TMates
Verified

Partner pharmacy: Not published

LegitScript: No badge found · FDA letters: none on file

What the medication actually costs

Both programmes price their own service. This is what a pharmacy pays for the branded drug underneath, so you can see what each one adds on top.

Tirzepatide
$1,077
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$992
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$995
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$871
pharmacy acquisition cost, lowest package
Aug 12, 2026
Tirzepatide
$1,052
pharmacy acquisition cost, lowest package
Aug 12, 2026

Source: CMS NADAC. This is what pharmacies pay, not a retail price and not what you would be charged.

Questions

Good to know

TMates starts at $199 per month. $199/mo semaglutide, $297/mo tirzepatide. Consultation is included and shipping is free.

Data sources · cited with retrieval dates

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.