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He & She MD vs Yucca Health

He & She MD and Yucca Health compared on real monthly cost, medications, states served and how each one verifies.

By Sam Reed · Founder and data lead
TL;DR — our verdict
Yucca Health rates higher at 9.3/10.
He & She MD
7.9/10
$149per month, from
+$3/mo vs Yucca Health
VerifiedVisit He & She MD
Yucca Health
9.3/10
$146per month, from
-$3/mo vs He & She MD
VerifiedVisit Yucca Health

Every line that matters

He & She MD
Yucca Health
Month-1 price
$149
$146
Month-2+ price
$149
$146
Three-month total
$447
$438
Membership fee
None
Not disclosed
Consultation fee
None
None
Shipping
Free
Free
Medications
Compounded semaglutide, Compounded tirzepatide
Compounded semaglutide, Compounded tirzepatide
Forms
Injection
Injection
Medication type
Compounded only
Compounded only
States served
49 states
All 50 states
Insurance
No
No
Partner pharmacy
Not disclosed
Not disclosed
LegitScript badge
Yes
Yes
Cancel anytime
Not disclosed
No
Our rating
7.9 / 10
9.3 / 10
Start today
Visit He & She MD
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= better value on that rowScroll sideways on small screens — the first column stays pinned

Real cost over three months

An introductory month makes a programme look cheaper than it is. This is the first month plus two at the standing rate, which is where the two actually separate.

He & She MD
Month 1
$149
Months 2–3
$149 × 2
Three-month total
$447
Yucca Health
Month 1
$146
Months 2–3
$146 × 2
Three-month total
$438
Quick pick

Which one is you?

Choose He & She MD if…
  • Users who want a true monthly plan before committing to a prepaid one
  • A true monthly plan with no commitment ($199/mo semaglutide)
  • Charged only if a provider prescribes
  • Pharmacy partner and chief medical officer are named
Choose Yucca Health if…
  • Users who want a LegitScript-certified provider with verified patient reviews and flexible financing
  • LegitScript certified — pharmacy and telehealth verified
  • 4.6/5 Trustpilot rating from 1,000+ verified patient reviews
  • Named physicians: Dr. Michael Wasef, MD and Dr. Andrew Sakla, DO
Safety

How both check out

He & She MD
Verified

Partner pharmacy: Not published

LegitScript: Certified · FDA letters: none on file

Yucca Health
Verified

Partner pharmacy: Not published

LegitScript: Certified · FDA letters: none on file

What the medication actually costs

Both programmes price their own service. This is what a pharmacy pays for the branded drug underneath, so you can see what each one adds on top.

Tirzepatide
$1,077
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$992
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$995
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$871
pharmacy acquisition cost, lowest package
Aug 12, 2026
Tirzepatide
$1,052
pharmacy acquisition cost, lowest package
Aug 12, 2026

Source: CMS NADAC. This is what pharmacies pay, not a retail price and not what you would be charged.

Questions

Good to know

Yucca Health starts at $146 per month. $146/mo month-to-month semaglutide, or $125/mo on the 6-month plan ($750 total); tirzepatide $258/mo month-to-month or $225/mo on the 6-month plan. Klarna/Affirm/Afterpay available.. Consultation is free and shipping is free.

Data sources · cited with retrieval dates

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.