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He & She MD vs Sesame Care

He & She MD and Sesame Care compared on real monthly cost, medications, states served and how each one verifies.

By Sam Reed · Founder and data lead
TL;DR — our verdict
He & She MD rates higher at 7.9/10.
He & She MD
7.9/10
$149per month, from
Same price as Sesame Care
VerifiedVisit He & She MD
Sesame Care
7.2/10
$149per month, from
Same price as He & She MD
VerifiedVisit Sesame Care

Every line that matters

He & She MD
Sesame Care
Month-1 price
$149
$149
Month-2+ price
$149
$149
Three-month total
$447
$447
Membership fee
None
$99
Consultation fee
None
None
Shipping
Free
Not disclosed
Medications
Compounded semaglutide, Compounded tirzepatide
Wegovy, Zepbound, Ozempic, Mounjaro
Forms
Injection
Injection, Oral tablet
Medication type
Compounded only
Brand-name and compounded
States served
49 states
All 50 states
Insurance
No
No
Partner pharmacy
Not disclosed
retail
LegitScript badge
Yes
Yes
Cancel anytime
Not disclosed
Yes
Our rating
7.9 / 10
7.2 / 10
Start today
Visit He & She MD
Visit Sesame Care
= better value on that rowScroll sideways on small screens — the first column stays pinned

Real cost over three months

An introductory month makes a programme look cheaper than it is. This is the first month plus two at the standing rate, which is where the two actually separate.

He & She MD
Month 1
$149
Months 2–3
$149 × 2
Three-month total
$447
Sesame Care
Month 1
$149
Months 2–3
$149 × 2
Three-month total
$447
Quick pick

Which one is you?

Choose He & She MD if…
  • Users who want a true monthly plan before committing to a prepaid one
  • A true monthly plan with no commitment ($199/mo semaglutide)
  • Charged only if a provider prescribes
  • Pharmacy partner and chief medical officer are named
Choose Sesame Care if…
  • Users with insurance who want cheap doctor visits — medication costs are separate and not included
  • Lowest consultation cost — visits from just $25
  • Prescribes brand-name FDA-approved medications
  • Transparent per-visit pricing with no subscriptions
Safety

How both check out

He & She MD
Verified

Partner pharmacy: Not published

LegitScript: Certified · FDA letters: none on file

Sesame Care
Verified

Partner pharmacy: retail, licensed in all 50 states

LegitScript: Certified · FDA letters: none on file

What the medication actually costs

Both programmes price their own service. This is what a pharmacy pays for the branded drug underneath, so you can see what each one adds on top.

Tirzepatide
$1,077
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$992
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$995
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$871
pharmacy acquisition cost, lowest package
Aug 12, 2026
Tirzepatide
$1,052
pharmacy acquisition cost, lowest package
Aug 12, 2026

Source: CMS NADAC. This is what pharmacies pay, not a retail price and not what you would be charged.

Questions

Good to know

Sesame Care starts at $225 per month. $25-75 per visit + medication at pharmacy prices ($200-1,400/mo). Total starting cost ~$225/mo with insurance savings cards. Medication NOT included in visit fee.. Consultation is $25-75.

Data sources · cited with retrieval dates

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.