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Enhance MD vs Sesame Care

Enhance MD and Sesame Care compared on real monthly cost, medications, states served and how each one verifies.

By Sam Reed · Founder and data lead
TL;DR — our verdict
Enhance MD rates higher at 8.3/10. Sesame Care is the cheaper way in at $149 per month, so it wins on price alone.
Enhance MD
8.3/10
$169per month, from
+$20/mo vs Sesame Care
VerifiedVisit Enhance MD
Sesame Care
7.2/10
$149per month, from
-$20/mo vs Enhance MD
VerifiedVisit Sesame Care

Every line that matters

Enhance MD
Sesame Care
Month-1 price
$169
$149
Month-2+ price
$169
$149
Three-month total
$507
$447
Membership fee
Not disclosed
$99
Consultation fee
None
None
Shipping
Free
Not disclosed
Medications
Compounded tirzepatide, Compounded semaglutide
Wegovy, Zepbound, Ozempic, Mounjaro
Forms
Injection
Injection, Oral tablet
Medication type
Brand-name and compounded
Brand-name and compounded
States served
41 states
All 50 states
Insurance
No
No
Partner pharmacy
Not disclosed
retail
LegitScript badge
Yes
Yes
Cancel anytime
Yes
Yes
Our rating
8.3 / 10
7.2 / 10
Start today
Visit Enhance MD
Visit Sesame Care
= better value on that rowScroll sideways on small screens — the first column stays pinned

Real cost over three months

An introductory month makes a programme look cheaper than it is. This is the first month plus two at the standing rate, which is where the two actually separate.

Enhance MD
Month 1
$169
Months 2–3
$169 × 2
Three-month total
$507
Sesame Care
Month 1
$149
Months 2–3
$149 × 2
Three-month total
$447
Quick pick

Which one is you?

Choose Enhance MD if…
  • Budget-conscious users interested in combination therapies
  • Affordable entry point starting at $115/month
  • Unique NAD+ therapy option alongside GLP-1
  • Board-certified physicians lead all protocols
Choose Sesame Care if…
  • Users with insurance who want cheap doctor visits — medication costs are separate and not included
  • Lowest consultation cost — visits from just $25
  • Prescribes brand-name FDA-approved medications
  • Transparent per-visit pricing with no subscriptions
Safety

How both check out

Enhance MD
Verified

Partner pharmacy: Not published

LegitScript: Certified · FDA letters: none on file

Sesame Care
Verified

Partner pharmacy: retail, licensed in all 50 states

LegitScript: Certified · FDA letters: none on file

What the medication actually costs

Both programmes price their own service. This is what a pharmacy pays for the branded drug underneath, so you can see what each one adds on top.

Tirzepatide
$1,077
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$992
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$995
pharmacy acquisition cost, lowest package
Aug 12, 2026
Semaglutide
$871
pharmacy acquisition cost, lowest package
Aug 12, 2026
Tirzepatide
$1,052
pharmacy acquisition cost, lowest package
Aug 12, 2026

Source: CMS NADAC. This is what pharmacies pay, not a retail price and not what you would be charged.

Questions

Good to know

Enhance MD starts at $249 per month. Semaglutide $249/mo; tirzepatide $379/mo; annual plans save ~15%. Consultation is included and shipping is free.

Data sources · cited with retrieval dates

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.