SkinnyRx review video: The $99 Shot Renews at $249, Plus an FDA Letter

0:00Intro + our verdict

SkinnyRx sells GLP-1 shots for $99. But that's the first month. After that, semaglutide renews at $249 a month... and tirzepatide at $299. And in February 2026, the FDA sent the company a warning letter. So let's work out what you really pay, how the sign-up works, and what the FDA wrote. Quick note: this isn't medical advice, and prices change, so check glp1.health for the latest. Our verdict first: 8 out of 10.

Good. You can pay month to month, with no contract. The drug, the clinician, and shipping come in one price, with no membership fee. And the terms spell out the refund rules. The catch? An open FDA warning letter... and we couldn't find which pharmacy makes its drugs.

0:51What SkinnyRx is

So what is it? SkinnyRx is an online weight-loss program, run by Lean Rx, Inc., in Sacramento, California. The menu: compounded semaglutide and compounded tirzepatide... each as a weekly injection, or a daily tablet. Wegovy and Foundayo pills are listed too... but after our intake, both showed as "Unavailable". The compounded plans aren't sold in Alabama, Louisiana, or Mississippi. By the way, if you want a GLP-1 pill, we compare the online programs for pills on one page. The link is in the description.

1:25The SkinnyRx sign-up

We walked the sign-up on November 4, as a new patient in Texas: about 35 screens. One says SkinnyRx only works with licensed compounding pharmacies... without naming one. The medical history asks about symptoms, and says "our version of GLP-1s contains an additive"... with no "None" option: you have to tick one. A compounded GLP-1 with vitamins or other additives is not the same as Wegovy or Zepbound, and hasn't been tested in trials.

Another screen says every application is "approved by a licensed provider within minutes"... and at the end: "Your intake has been accepted!", with a countdown to check out. On October 27, it even said "your protocol is reviewed and ready"... Before any clinician had seen it.

2:09What it really costs

Then come the plans. Every shot plan shows "$99 first month". Read the line under it: "Then $249 a month" for semaglutide, on the 1-month plan. The payment page spells it out: $99 today, then $249 every month. Tirzepatide shots: $99, then $299 a month. The tablets start at $149 for semaglutide, and $199 for tirzepatide... and both renew at $299. Semaglutide shots drop to $199 a month on the 12-month plan... but that's $2,287 charged at once, renewing every year at $2,388.

So what does a first year of semaglutide shots cost? Month to month: $99, then 11 months at $249. That's $2,838. On the 12-month plan, it's $2,287, up front. The checkout says that plan saves you $1,900. That figure starts from a struck-through price of $349 a month. Against SkinnyRx's own monthly plan, the saving is $551. And tirzepatide shots? Month to month, a first year comes to $3,388. The rest is simple. No membership, consultation or shipping fee.

The same price at every dose. No insurance, but it takes HSA and FSA cards. Watch the add-ons at checkout: Booster Capsules, at $60 a month... and a Metabolic Health plan with a glucose monitor, for $149 a month more. At $249 a month, month to month, SkinnyRx ranks 30 of the 45 compounded programs we track... well above the median of $165.06.

4:05Who makes the drugs + FDA warning letter

So who makes the drugs? The sign-up says a "State-licensed 503A Compounding Pharmacy". But we couldn't find its name: not on the site, in the terms, or in the sign-up. Without a name, you can't look it up in any public record. The product pages say its partner pharmacies run third-party tests through DEA-compliant labs... with four tests, each marked "Passed". We couldn't find which lab, which batch, or a dated test result...

not on SkinnyRx's site, and not in a web search on November 6. By the way, we rank the programs that name their pharmacies on one page. The link is in the description. Now, the FDA record. On February 20, 2026, the FDA sent a warning letter to Lean Rx, Inc., doing business as SkinnyRx. The letter says the drug labels pictured there showed "SkinnyRx", suggesting it made the drugs... "when in fact it is not." It quotes claims such as "It contains the same active ingredient as FDA-approved medications"...

and says: "Compounded drug products are not FDA-approved." It asked for an answer within 15 working days, with steps such as naming who produces the drugs. On November 6, we couldn't find a response letter or a close-out letter on the FDA's site. Today, the vial on the product page reads "Compounded Semaglutide Injection"... and we couldn't find the quoted claims on its home or product pages. LegitScript certifies SkinnyRx.

But it still names no pharmacy. The bigger question with any compounded program is the drug itself. Compounded GLP-1s are prepared by a pharmacy to a prescription. They are not FDA-approved: the FDA doesn't review their safety, effectiveness or quality before they're sold, and they are not the same as Wegovy or Zepbound. Formulas can differ from one pharmacy to the next, and some add ingredients such as vitamin B12.

Compounding pharmacies are licensed and inspected by state boards of pharmacy. Outsourcing facilities, called 503B, also register with the FDA and are inspected by it. Compounded semaglutide and tirzepatide have no label of their own. Their safety information comes from the labels of Wegovy and Zepbound, including a Boxed Warning about thyroid C-cell tumors.

6:23How the care works

After checkout, a licensed clinician reviews your intake. SkinnyRx says the prescription can be written within 24 hours, after a quick video visit in some states. The order ships within 2 business days, free. Each month, a refill form gets you the next supply. In between, you can message the care team through the patient portal, at no extra cost. There's an app too, by LeanRx. On November 6, Apple's App Store showed 4.7 stars, from 545 ratings.

And if you already take a GLP-1: brand-name and compounded products are not interchangeable. Your provider sets your starting dose.

7:01Cancelling, refunds + the 90-day guarantee

Canceling is easy: in your account, through the help center, or by phone. The date to watch is the renewal. The terms say your plan renews unless you cancel at least 5 days before the renewal date... and a renewal can be charged up to 5 days early. Before a provider finishes your review: a full refund. If the provider turns you down: a full refund within 24 to 48 hours. Once your order is in fulfillment: no refund, and none for a part-used month.

And the 90-day money-back guarantee? It pays only if your weight at day 90 is the same as, or above, your starting weight... after 90 paid days in a row, with your weight and every dose logged in the app each week. So here's the simple rule: if you're unsure, cancel at least 5 days before your renewal. And if you have side effects, talk to your provider.

7:52Reviews + who it's for

SkinnyRx's homepage shows a Trustpilot score: 4.8 out of 5, from 5,401 reviews. We checked Trustpilot on November 6. It shows the same: 4.8, from 5,401 reviews. SkinnyRx claimed the page in 2024, and invites its customers to review. So, who's SkinnyRx for? It suits you if you want compounded semaglutide or tirzepatide as a tablet, or as a shot... if you want to pay month to month, with no contract...

and if you want a full refund when a clinician turns you down. It's not for you if you want to know which pharmacy makes your drug... if you want a program with no open FDA warning letter... or if you want to pay the median price or less.

8:39Alternatives + 3 things to remember

Here are three, each with no FDA warning letter on file, and each names its pharmacies. Embody scores 9.6. No membership fee, and about $86 a month, month to month. SnagRx scores 9.2. It ships to 49 states, and it names its four pharmacies. And Lttl scores 9.0. It serves all 50 states, with an address for each of its four pharmacies. So, three things to remember. One: the $99 is the first month. Semaglutide shots then renew at $249 a month, and tirzepatide at $299.

Two: SkinnyRx has an open FDA warning letter, from February 20, 2026, and we couldn't find which pharmacy makes its drugs. Three: to stop a renewal, cancel at least 5 days before it. The full review, with every source, is one tap away. The link is right below, in the description... or scan the code on your screen. This video is educational, and it's not medical advice. Talk to a licensed clinician before you start, stop, or change a medication. Thanks for watching.