Medicaid reimbursed at least $11.95 billion for GLP‑1 drugs in 2025, before rebates. California paid $3.46 billion of it.

Medicaid GLP-1 spending hit at least $11.95 billion in 2025. California's share was 28.9%. A state-by-state ranking from CMS State Drug Utilization Data.

Published Sep 21, 2026 · Updated Sep 21, 2026

Quick answer

Medicaid programs reimbursed at least $11.95 billion for GLP-1 drugs in 2025, according to CMS State Drug Utilization Data. The figure is before rebates, so the net cost is lower, and it is a floor because CMS suppresses small cells. California paid $3.46 billion, 28.9% of the national total, and no other state passed $1 billion. Most of these drugs treat type 2 diabetes, so the total is not a weight-loss figure.

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Medicaid programs reimbursed at least $11.95 billion for GLP-1 drugs in calendar year 2025.2 That figure comes from the national rows that CMS publishes in its State Drug Utilization Data.1 It is a pre-rebate figure, and it is a floor. Both points matter, and this page explains each one.

California paid $3.46 billion, which is 28.9% of the national total.2 No other state passed $1 billion.2

What the number counts

CMS publishes one row per drug code, per state, per quarter.1 We sum the column total_amount_reimbursed for 40 GLP-1 drug codes across the four quarters of 2025.2 The drugs are Ozempic, Wegovy, Rybelsus, Mounjaro, Zepbound, Trulicity, Victoza, Saxenda and Byetta.1

The total holds two parts. Medicaid itself paid $11.73 billion.2 Other payers on the same claims paid $213.1 million, which is 1.8% of the total.2

The total covers 11,049,588 reimbursed prescriptions.2 A prescription here is one fill, not one patient.

Most of these drugs treat type 2 diabetes. This data does not say why a drug was prescribed, so the total is not a weight-loss figure.

Two limits on the number

It is before rebates. Drug makers pay rebates to the states after the pharmacy is reimbursed, and the utilization data does not show them.3 The net cost to Medicaid is lower than $11.95 billion.2 CMS does not publish the rebate per drug, so nobody outside the program can compute the net figure.3

It is a floor. CMS hides the values in small cells to protect patient privacy.1 In the state rows for 2025, CMS suppressed 1,970 of 8,939 rows, or 22.0%.2 A suppressed row adds nothing to a sum. Every state total on this page is therefore a minimum, not an exact count.

CMS suppresses less at the national level: 26 of the 280 national rows.2 The national rows carry $8.7 million more than the state rows and Puerto Rico added together.2 Puerto Rico reported $50.4 million.2

The ranking

The 50 states and DC sum to $11.89 billion.2 The shares in the table below use that sum as the base. The last column shows how many of the state's rows CMS suppressed.

Five states hold 55.6% of the state sum: California, Pennsylvania, New York, Michigan and North Carolina.2 The top 10 hold 70.1%.2 The bottom 10 hold 1.5%.2

Medicaid GLP-1 reimbursement, top 10 states, 2025 · $M · as of 2025 Q4

California's total is 3.6 times Pennsylvania's, the state in second place.2 California runs the largest Medicaid program in the country, so a large total is expected. This ranking is in dollars, not dollars per resident. Do not read it as a measure of how generous a state is.

Twenty-two states passed $100 million.2 Seventeen states stayed under $50 million.2 Texas ranks 17th with $178.1 million and Florida ranks 21st with $127.7 million.2 Both are large states with small totals. Population alone does not set the order.

RankStateReimbursed, 2025Share of state sumRows suppressed
1California$3,455.7M29.1%17 of 233
2Pennsylvania$950.2M8.0%31 of 250
3New York$936.4M7.9%37 of 167
4Michigan$680.3M5.7%13 of 248
5North Carolina$588.9M5.0%29 of 242
6Ohio$404.6M3.4%48 of 238
7Massachusetts$404.4M3.4%11 of 249
8Wisconsin$326.2M2.7%2 of 124
9Illinois$297.5M2.5%20 of 195
10Missouri$284.8M2.4%7 of 122
11Minnesota$251.9M2.1%21 of 247
12Kentucky$237.6M2.0%33 of 198
13Louisiana$230.3M1.9%33 of 173
14Virginia$228.0M1.9%75 of 242
15Indiana$204.0M1.7%41 of 229
16Connecticut$202.5M1.7%6 of 107
17Texas$178.1M1.5%77 of 185
18Tennessee$143.1M1.2%7 of 124
19Maryland$141.3M1.2%45 of 193
20New Jersey$132.7M1.1%65 of 181
21Florida$127.7M1.1%40 of 182
22Colorado$125.3M1.1%40 of 226
23Arizona$96.9M0.8%47 of 157
24West Virginia$91.3M0.8%32 of 111
25Iowa$87.1M0.7%65 of 193
26Oklahoma$82.8M0.7%26 of 193
27Nevada$81.2M0.7%44 of 210
28Alabama$71.9M0.6%14 of 109
29Mississippi$70.5M0.6%62 of 219
30South Carolina$64.9M0.5%49 of 217
31New Mexico$64.1M0.5%75 of 193
32Oregon$63.3M0.5%62 of 218
33Washington$61.0M0.5%69 of 198
34Kansas$53.3M0.4%9 of 116
35Georgia$49.6M0.4%35 of 203
36Rhode Island$48.8M0.4%61 of 221
37Idaho$46.0M0.4%6 of 113
38Maine$40.4M0.3%16 of 123
39New Hampshire$37.3M0.3%50 of 161
40Nebraska$36.1M0.3%22 of 110
41Hawaii$33.5M0.3%33 of 112
42Utah$28.3M0.2%69 of 196
43District of Columbia$27.9M0.2%51 of 186
44Montana$22.0M0.2%26 of 106
45Alaska$21.9M0.2%68 of 152
46Delaware$21.3M0.2%54 of 165
47Vermont$18.5M0.2%20 of 115
48South Dakota$15.6M0.1%14 of 78
49Arkansas$15.4M0.1%88 of 218
50North Dakota$2.5M0.0%50 of 76
51Wyoming$2.2M0.0%55 of 115

Source for every row: CMS rows, summed by glp1.health.12

Small states and suppression

Read the bottom of the table with care. Wyoming shows $2.2 million, but CMS suppressed 55 of its 115 rows.2 North Dakota shows $2.5 million with 50 of 76 rows suppressed.2 Arkansas shows $15.4 million with 88 of 218 rows suppressed.2

Suppression hits small cells, so it hits small states hardest. The true totals for these states are higher than the table shows. We cannot say by how much.

At the top of the table the effect is small. California lost 17 of 233 rows.2

The year by quarter

National reimbursement rose through the first three quarters and then eased.2

QuarterReimbursed
2025 Q1$2.63 billion
2025 Q2$2.80 billion
2025 Q3$3.32 billion
2025 Q4$3.20 billion

The third quarter was 26.3% above the first.2 CMS revises recent quarters as states file late claims, so the fourth-quarter figure can still move.1

Which molecules the money bought

MoleculeReimbursed, 2025Share
Semaglutide$6.61 billion55.3%
Tirzepatide$3.32 billion27.8%
Dulaglutide$1.95 billion16.3%
Liraglutide$0.07 billion0.6%

Semaglutide took 55.3% of the national total and tirzepatide took 27.8%.2 Exenatide rounds to zero.2

How to cite this

Use this sentence: "Medicaid reimbursed at least $11.95 billion for GLP-1 drugs in 2025, before rebates, according to CMS State Drug Utilization Data summed by glp1.health."2

Keep "at least" and "before rebates" in the sentence. Without them the number is wrong.

For the Medicare side, see Medicare Part D GLP-1 spending.

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Compare verified prices for GLP-1 treatment from online programs.

Data sources · cited with retrieval dates
  1. 1.
    CMS State Drug Utilization DataMedicaid reimbursement rows per drug code, state and quarter. Calendar year 2025, all four quarters, 40 GLP-1 drug codes.Centers for Medicare & Medicaid Services↩
  2. 2.
    glp1.health warehouse, Medicaid GLP-1 sums by stateSums, ranks and shares computed by glp1.health from the CMS rows. Data loaded in August 2026. National figures use the CMS national rows. State figures use the state rows.glp1.health↩
  3. 3.
    Medicaid Drug Rebate ProgramManufacturers pay rebates to states after the pharmacy is reimbursed. The utilization data does not show these rebates.Centers for Medicare & Medicaid Services↩

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.